Government approves first Covid-19 vaccine for children above 12 years

印度政府批准首款针对12岁以上儿童的新冠疫苗

NEW DELHI/MUMBAI: Zydus Cadila's India-developed anti-Covid jab ZyCoV-D secured regulatory approval on Friday for emergency use, becoming the world's first DNA-based vaccine for the novel coronavirus that will be administered to children above 12 years and adults.

新德里/孟买：周五，Zydus Cadila在印度研发的新冠疫苗ZyCoV-D获得了监管部门的紧急使用许可，成为全球首款基于DNA的新冠疫苗，可用于12岁以上儿童和成人。

The company has indicated a supply of around five crore doses by December, a senior official said. The delivery of vaccines is likely to begin by next month-end. The DNA-based vaccine is the sixth shot to receive approval in India.

一位高级官员说，该公司表示，到12月将供应大约5000万剂。疫苗的交付可能在下个月底开始。这种基于DNA的疫苗是在印度获得批准的第六种疫苗。

While the government is yet to sign a final agreement with Cadila, supplies to the national programme are set to be augmented.

虽然政府还没有与Cadila签署最终协议，但对国家计划的供应将会增加。

To start with, the company will supply around one crore doses in a month. Pankaj R Patel, chairman, Cadila Healthcare, told that the vaccine showed 66% efficacy against moderate Covid infection and 100% against severe Covid, preventing serious disease and hospitalisation. The clinical trials were conducted on over 28,000 subjects, including kids, and were done when the Delta variant was prevalent across the country. This has been the largest vaccine trial so far in India for Covid-19.

首先，该公司将在一个月内提供大约1000万剂疫苗。Cadila Healthcare董事长Pankaj R Patel表示，该疫苗对中度感染的有效性为66%，对重度感染的有效性为100%，预防重症和住院治疗。临床试验在超过28000名受试者中进行，其中包括儿童，而且是在德尔塔变种在全国流行的时候进行的。这是印度迄今为止规模最大的新冠疫苗试验。

According to the WHO, DNA technology is a radically new approach to vaccination that involves direct introduction of a plasmid containing the DNA sequence encoding the antigen (in this case the Covid virus) against which an immune response is sought. "This approach offers a number of potential advantages over traditional approaches, including stimulation of both B and T-cell responses, improved vaccine stability, absence of any infectious agent and the relative ease of large-scale manufacture," says the WHO.

据世界卫生组织介绍，DNA技术是一种全新的疫苗生产技术，包括直接引入含有编码免疫应答的抗原的DNA序列的质粒。世界卫生组织说：“与传统方法相比，这种方法提供了许多潜在的优势，包括刺激B细胞和T 细胞反应，改进疫苗的稳定性，没有任何传染因子，以及相对容易大规模生产。”

The three-dose Zydus vaccine, developed in partnership with the department of biotechnology, has been approved with a dosage cycle where the second and third shots will be administered at an interval of 28 days and 56 days, respectively, from the first dose.

与生物技术部门合作开发的三剂Zydus疫苗已获批准，第二剂间隔时间为28天，第三剂间隔56天。

以下是印度时报读者的评论：译者：Jessica.Wu

Dhirendra Shukla

Great job done Zydus. Since this is the only jab proven safe and effective for children, it should be reserved for children only. Children need to resume attending classes as early as possible to ensure they do not miss their all important studies at this age.

干得好，Zydus。这是唯一经证实对儿童安全有效的疫苗，只留给儿童接种。孩子们需要尽早恢复上课，别耽误学习了。

Boss

Absolutely right suggestion. Govt must reserve this for 12 to 18 age children

太好了，政府必须为12到18岁的孩子保留这些疫苗

Asok Datta

Our children must be protected immediately and this vaccine seems to fit well- great job by Zydes

我们的孩子务必立即获得保护，这种疫苗似乎很适合——Zydes做得好

Vj Lion

Great job by Indian scientists, Hail Modi ji.

印度科学家干得好，莫迪万岁。

bhartiyabharat21

hope for best..

希望效果好。

Sanjay Sehgal

DNA vaccine makes it most scary.

DNA疫苗最可怕了。

Aneesh Raman

Bengaluru, Gujarat, Pune and Hyderabad are the cities in India that have the highest concentration of Bio-tech and Pharma companies. And this has been so for at least a couple of decades. Why this skewed concentration is a completely different question that needs to be addressed by states that have failed to attract pharma companies. No country has an equal distribution of industries all over their region.

班加罗尔、古吉拉特邦、普纳和海德拉巴是印度生物技术和制药公司最集中的城市，这种情况至少已经持续了几十年。那些未能吸引到制药公司的邦要解决这种分布不均的问题。但没有一个国家的工业分布是平均的。

Jasdeep Singh

Why pfizer is not available here?

为什么印度没有辉瑞疫苗？

Kapil Gupta

why u need ...domt u trust indian scientist

为什么你要辉瑞疫苗？…难道你信不过印度科学家？

Anurag Bajpai

Facts- Very low efficacy against delta variant, already needing booster in Israel, need for very low tempuratire to store.

事实上，辉瑞疫苗对德尔塔变种的有效性很低，在以色列已经需要打加强针，需要很低的温度储存。

Indrajit Banerjee

Why do you want Pfizer? $30/- per shot and the cold-storage chain requirements are you aware of them? Can you provide those?

你为什么想要辉瑞疫苗？每剂30美元，还需要冷库链，你知道吗？你能提供这些吗?

Sanjoy Pandey

At least children above 12 years should be vaccinated with this jab first, to restore the education system.

至少12岁以上的儿童应该首先接种这种疫苗，学校才能重开。

Vidya Shenoy

This is the first covid 19 vaccine given without needle.in the world.No pain.Please reserve it for children only

这是全球首个无针注射的新冠疫苗，不会痛，请为儿童保留

Shrikant Satwe

Great News!! Modiji hai to Mumkin hai

好消息！莫迪让一切变得可能！

bhartiyabharat21

Gujrat ahmedabad company got approval.

古吉拉特邦艾哈迈达巴德的公司获得批准。

Hari Sud

Bravo, it is a great achievement.

太棒了，这是一个伟大的成就。

Rv Sagar

three dose regimen with an availability of 5 cr doses till Dec is peanuts and would put the government under pressure.

要接种三剂，直到12月才能提供5000万剂，太少了，政府会感到压力的。

Aneesh Raman

Better to see it as 5Cr doses that can be administered to at least 1.5Cr children above the age of 12.

5000万剂，12岁以上的儿童才1500万。

Parthadeb Chakravorty

kudos to Indian scientists and the government for making this happen.

向印度科学家致敬，让这一切成为现实。

Dilip Rathod

stupendous achievement, Zydus Cadila! Atmanirbhar Bharat

伟大的成就，Zydus Cadila公司！印度自力更生！

Nandkishor Kothari

Better late than never

迟做总比不做好

Akash Patel

Slow

太慢了